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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53769d01c5f33c45f0302cf1f0df6e84137563089e423ffee776d60884945011' 
  AND token = 'nVOi/Fl2f8XV8J3PjGOOrE8hFjrdNselJgM8RCx3Srg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}