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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26ab45cb19e6c0dbc3a148ef8d09fe850465515fd8e35807bf9a871dc727b686' 
  AND token = 'Lcd3tvuQNbi+fWCL1uy06IAfvTCoycgudBcT+172fKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}