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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad64a2eae7e2b46e83582f6919ca446b123e7f2a1383204f26d8c008a9484433' 
  AND token = 'qH9R9cR2ddVKAfX+8hleEdv7Bl6hkAwcylOfhoYLuZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}