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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11040651c5933f7e3d06e45722d3b3832e4b0d6c410687a3f9a4133e6b67cd50' 
  AND token = 'M5/8EqCqiFTQvhyYVMTiGxHxKS1ojK0YFvyXSCyehDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}