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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e484cdd787ff75f17080174e37eb3feabcfab1d8a46a5a74684f7c6603bc127f' 
  AND token = 'an6xk8auL1d1k6kCqJzeVQnraf+LzW53zk7+cZf4HUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}