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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50d3d25d39570e18a418fa716f8f8b3ea91cfaef047638c0724decf73daec1ac' 
  AND token = 'HwuLEBo/v8FYQJGeE+WABP000Vd7p1rK1tBqrg7M8VY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}