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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3a885c4c4fc2463fb568bdf9d345cd6802e3a0bbd43d689ec5296a234a014c5' 
  AND token = 'jj8PEM6r3VhnM+Rj7ZqmRrMnKwgVw+oXdGQac9j8Tyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}