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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb6d16566397b0b700c4c22fd349fe0d99e28e731a301ec56e914c9dd6480cf' 
  AND token = 'F9QIlXCQxNYqlPwDP04IIx7UYycQLGuSLYz32Gg4MbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}