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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489ebf246ef9c204e289c09aea8555788d99fc6280c3bc32d00692542c30994c' 
  AND token = 'Er4lXlP1BoEmlaPvitum/iPreFeNv/AB5tEHZcP/MB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}