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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5fb05bb6af4f6f38749c98a3cd1033f7328da1664d86fad3c261b088da27878' 
  AND token = '6GyDTF3Uhl3PgqglvC1vcc2BQ3DVk0IstCf+maMsbXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}