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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f7291fdc3e1dc999b94e0adba3db58b5f90c8c046314d0a3a45a7402620b4f8' 
  AND token = '0eS8YQLmJ+D7fBNZbXiFCosi8RWlnWwf1ZAty0Vd/LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}