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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdb5d2a886cea7c3589f2d0b71acf1ee5f9646f0f11364a0c674bef57e8ab441' 
  AND token = 'w/46+9itZESjIwoOsNE6HxMGvEFa5wuQPzNF0TwFel4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}