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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3b9782d0cf70f2a381d73887246d063dbca84b0b8e924755ef6780205a68456' 
  AND token = 'J/fe4U/M67t2FLVrEf5VHpwYXsD9iE3wB9jgnaMOfRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}