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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '460951a50c527987d62c2036e73bafb372ffc8c1ff202e8747493ef4c3e665d6' 
  AND token = 'xD4n6cPkIeWrYqHpPFR0ivsbvsEJAgZvcGvMbfODmJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}