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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3085fdcdc9e28271ab859fc6b5964b058cafc613f0b2108ff8e064a761a2aef1' 
  AND token = 'S+hMm4FP6b+EMWpdniuDFkZgxmA7TPLpf2bh26UGxlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}