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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ae6428743f5adf1894c017933ea268300ed864e8db134470610ed5b2f3754b' 
  AND token = '21Ght+o8mKA9T1f6UiatMxFd/JPHac6XzKMTecFRKZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}