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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d65a7ca0b016cf8727fb818f2d8c5a4bc882bca5f24dd4e1c2f490a5b8caf54' 
  AND token = 'lsSU1nOrd/AUoLOqnsbJe12GnQtJ17NoyT5PlT82rPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}