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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de5f51d5198ce8a169b9b64a7616698f692b9e46a0d7f14f2a671099a1e0952' 
  AND token = 'LqGbyG4LD9Tp48PS9Qha6yKv9RUMy7yy1qDXnHMIoU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}