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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7c48769e60eee50aca2bffa192e5492d3a625e58f980b205ebb4583954cb1fd' 
  AND token = '3oWMn4qYs01KgwxtKwQ40gMO2hY9f9PTJTO4r9XP/Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}