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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1de7727157a698b4d49441e32db1b361b58023944a7ca624a47edda6de46905' 
  AND token = 'YD1PuyCTmBTYuMniPg/SonRtNKRE7gHGJv+9CrF5j+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}