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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '730a594a1c47894e53a4d3033232a1135547f6bf36156b017cfdd02e04aefaa3' 
  AND token = 'lN37NeJtSCmudGQDfKOsFu/E8g39BYeU7rE+S+cRKrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}