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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7e155d75ad6355e3c83560c00a73b058c9420ad12f60cef9defe13fc34fca5' 
  AND token = 'IhgHlweTgL5KIzCWGyDf3m3HPqMuWaPuBct4R2uWcR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}