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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a9d361ed91a577b37abe12deb3539fec77baec28034bf25e2778bef683f40a9' 
  AND token = 'k7+bEgiAwRDjmPCak1D0FK+2SWnwcataE0wGgplBaoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}