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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459537a4290b97e03505a070edcb437713163e710faf055a7c0167008151ea00' 
  AND token = 'NxsqF1Dn6Vt31lowvm45TNdAfwyb8wvs8dI9wGGtF1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}