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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9423876829cf273041232921a64d3f5378fba8148bc0a88cbc615ca5e0bf69e6' 
  AND token = 'bJkkk77T38wtwM1J4o2lu/GAldN8d002Owh9NQLpoTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}