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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7bc8ea0345d1a564ba24e04bcdb86f6615a3e642996b0be5b49387f7d403610' 
  AND token = '9SOFxyBxEk07FH/Ft8TPK7YsWKeSquaCf0bkDHIZdF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}