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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f6fda188e9beb9be4ea9e5ac4520d45f3aef9ef170616edbb705bf522dcc891' 
  AND token = '3QHiakChiDS1O/S38k6qQ8y+2sjeQ3sa93iLy3Nv3S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}