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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80bb1aeca204f9e9b4c674fe401529dbedd9e5c23c464c3a718814ad00658e14' 
  AND token = '5urW+osj6KNZB1bIgCElqukRqxopBGrninN/vh9no10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}