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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '518545099ba09b34562ef3ceb0b7fb0e130c5964a86f8c697689bb34f4b4e039' 
  AND token = 'RF/ct8xeLH3WCWkDYh/8yrXI42zGqZgDdr6eB5TyWEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}