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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c48f0e894bf811b17a556b0e3027bbea474ef484c3b1e4d4738b892dcc1947d9' 
  AND token = 'AYFErMqKgMD9yGxYqAeCmHqC/xKm5xQU5EWjxLpD3hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}