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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d1e8d9ac06800fa32555c5a686657a67b61ede776044882114c226afab2009a' 
  AND token = 'fAp3CCvNWCJ+j9NCSXThcWjcQgh2rOD8vTLrwpC+ACI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}