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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d8657eaceb5023f173dc3f1f33b970b30eb8dcd3e63ef0e6f8537bcf8159c7' 
  AND token = 'HDJFocYi7s6kdpMTa3qLLbll9AJ0rcE4XIbUld3AAaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}