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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0cd45c61d0f5032f9476f6629affc12d2eed8f2f9182166f728568eb063984c' 
  AND token = 'bro6IRIlRddw3oqxQ1/EArmAeoWoZxx9/EGagIT8F84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}