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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '760a4a39cc126868a379a04c2c772f3ef51409d683cef7260cd850a600243c20' 
  AND token = 'x1OTFP3yTEUwnDU5pjfTe9O21RdE0mFMUmjeRdQVpkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}