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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b77aea561f23a77ef0b2f192e31180dd908a8bdb8e69d0a67d9c31edc753924' 
  AND token = 'zUdoC1o7Gtaxl+FWV+wMTxyWdDvrAqnmazDr2NjDQgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}