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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '108a1187e010499727892dcdf07334e1f9f31bda5cc26ad9e25f1b118365e0ca' 
  AND token = 's+6053tt6pDWeNO3UATsD+AstBtmTujv9Gs51X93eI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}