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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b20d9e603247892e2b8545e853765e69f3d5ee391f0a0e0e23d2175428624cd' 
  AND token = 'EHIfSBdkoiMeS+RgexWUK97egdOhNcZ8cYvCmYu/Dns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}