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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae0ed1a66b82f47c62289b58594358d4d21918f9bb0c2612c28ed5abc8270a89' 
  AND token = 'JeCUA4p0VpoAvL9ir0csHZxiy4+/pebaOoVi/cAB7yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}