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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58243b6328ed8c3d035c9c104713dc15c731278fb6fa0858459ff4a0160f0d17' 
  AND token = '6KnN+zM81oIeZV0qfDKtCuEzrvFMrP/8pN+ioW2KlSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}