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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '138b9920d815fcbfc401c901fd6f5405403c10c41ec2ed15703eb90ff5ffbb3c' 
  AND token = 'hl/XhN5ivr5SEzD0sN+sOMBwsDXSpQOkp2dz/cQviSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}