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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a6e1e27c8d2d9d419058e70eadc5805c03e49b2c0495e194a2a26c0d86434d9' 
  AND token = '+MOsEQvQj/vw4+QNC3Tvvy7Ia9uaGKWt06ejU+HoY9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}