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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728917bca6e2d51cd43e2345f7beb9e1d5650ae87c992a81d28ad79193267e29' 
  AND token = 'PGSsFFolBk5G5m0jY4RLfbo2h1X3W3rbJl3sg8CaD2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}