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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39a196d392f983794a94f85c0aa5ed538b6f7129957502ed16a10f4b1c99c379' 
  AND token = '+Ui08Q6Ti4uotF1sVF5dcltwn0depgxVgmsiRZQ8Vro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}