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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c44e6d3bec36e60edf21a2f54c1afdbf27eb91354e4d64783801648ee228cd9' 
  AND token = 'e65QXCtrVlQJncoBrngLIVrvSifZHIHvQTmBgj17mPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}