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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '740bda72232c31731b24acc8f763023c9fd2cd8776f12284a3a1f2efa9e4949f' 
  AND token = 'oX/JOyvXtBndgO91ERNw22zMGkH+CEYGWECb9c2JXHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}