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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '985375b7e5d2a121cc93a0b63aed0a237df00bc34c56c4fb0561a9d638c8fb64' 
  AND token = '4lSy+ol2BclMkPwSwHUbprMDI5Hm6FoBeYXiqiIEB3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}