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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b38943c4b94fee48772b8376575fe3e84e0822bf59b1ea9e450979c5943ec67' 
  AND token = 'FkuJYmEflZYQ1AMGi21G0YwNtzZKdzNh8UvZvomE6P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}