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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c9a8139e911c80c1aeb850ebfd3684a307efc7ea3fd64f47ff252f327eff91' 
  AND token = 'insqAijR6XU2IpMHOXegSJs5gESvz8BrmwZFbf8h0Pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}