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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd75daff2cf8518ce6cfedf13b6125b8b6cfb24c6f62cad94529b9759c353e947' 
  AND token = 'UxCBV+Fq6qL09uuSoTMlUBABoFp1/RMWcTqOXS0JdJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}