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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4289366370c656e3366085d160c8ca0e1b17f23e25f14a19479a3c4a95f7a79' 
  AND token = 'uQ1UC9HEDiY17yr3UF2AdoUOeyyJ/A8JlGftUUeRHe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}